http://www.sciencecases.org/sickness_and_health/sickness_and_health.asp
1. Do autosomal dominant disorders skip generations?
-Yes it is possible to skip generations but not likely.2. Could Greg or his mother be carriers of the gene that causes myotonic dystrophy?
-No
3. Is there a possibility that Greg’s aunt or uncle is homozygous for the myotonic dystrophy (MD) gene?
-Yes
4. Symptoms of myotonic dystrophy sometimes don’t show up until after age fifty. What is the possibility that Greg’s cousin has inherited the MD gene?
-Pretty good
3. Is there a possibility that Greg’s aunt or uncle is homozygous for the myotonic dystrophy (MD) gene?
-Yes
4. Symptoms of myotonic dystrophy sometimes don’t show up until after age fifty. What is the possibility that Greg’s cousin has inherited the MD gene?
-Pretty good
5. What is the possibility that Greg and Olga’s children could inherit the MD gene? -- Absolutely not
Recessive
- What are the hallmarks of an autosomal recessive trait?
-Skips generations
2. What does consanguineous mean? Why is this concept especially important when discussing recessive genetic disorders?
-Consanguineous is being of the same family or blood connection. This is important because it can explain who and where it came from and stop the possible inheritance in further generations.
3. What is it about the inheritance pattern of factor VIII deficiency seen in Greg and Olga’s pedigree that point toward it not being an autosomal recessive trait?
3. What is it about the inheritance pattern of factor VIII deficiency seen in Greg and Olga’s pedigree that point toward it not being an autosomal recessive trait?
-In Greg and Olga's pedigree it is proven that it cannot be an autosomal recessive trait because two generations back to back are both carriers of the disease.
SexLinked